Sertaconazole vs. Clotrimazole Vaginal Suppositories for Treating Vaginal Candidiasis in Pregnant Women: A Randomized Trial

A double-blinded, randomized trial found that a single dose of sertaconazole (300 mg) was as effective as clotrimazole (500 mg) in treating acute vaginal candidiasis during pregnancy. Both treatments showed comparable clinical and microscopic cure rates, patient satisfaction, side effects, time to recovery, recurrence rates, and pregnancy outcomes. The study highlights sertaconazole ovules as a viable alternative to the traditionally used clotrimazole vaginal tablets for managing vaginal candidiasis in pregnant women.