Description
Third-generation cephalosporins represent a vital class of antibiotics in modern medicine, prized for their broad-spectrum activity against both Gram-positive and Gram-negative bacteria. One of the hallmark features of third-generation cephalosporins is their enhanced ability to penetrate the blood-brain barrier, making them invaluable in treating central nervous system infections. This CME explores Ceftriaxone, a 3rd generation cephalosporin, growing resistance against it, increasing ESBL presence in Nigeria, and a combination therapy as a potential alternative.