The oral route remains one of the most preferred methods of drug administration, and within it, orally dispersible tablets (ODTs) are gaining growing attention for their ease of use and patient-friendly design. These tablets are particularly beneficial for pediatric, geriatric, bedridden, and mentally ill patients, as well as those who face difficulty swallowing conventional dosage forms.
ODTs are designed to disintegrate or dissolve rapidly in the mouth, improving patient compliance, convenience, and bioavailability. Their quick action and non-invasive nature make them a promising alternative to traditional oral tablets.
Recent studies highlight a number of drugs successfully reformulated as ODTs, demonstrating strong in-vitro and in-vivo performance. A comprehensive review further explores the advantages, limitations, ideal properties, formulation methods, and evaluation parameters of these innovative dosage forms—offering researchers a concise overview of this rapidly evolving technology.